Cystoid macular edema associated with fingolimod use for multiple sclerosis.
نویسندگان
چکیده
Fingolimod is the first oral drug approved by the US Food and Drug Administration for multiple sclerosis (MS). It is a sphingosine-1phosphate–receptor modulator that prevents lymphocyte egress from lymph nodes and enhances astrocyte function. In this retrospective case series, 4 eyes from 3 patients developed cystoid macular edema (CME) after initiating fingolimod therapy. The study was approved by the University of Chicago Institutional Review Board.
منابع مشابه
Acute Anterior Uveitis in a Patient Taking Fingolimod (FTY720) for Multiple Sclerosis
Fingolimod is an oral sphingosine-1-phosphate (S1P) receptor modulator and the first oral therapy for relapsing-remitting multiple sclerosis. Its use has been complicated by a low rate of cystoid macular edema usually in the first 3 months after commencement of the medication. We report the case of a 34-year-old male with relapsing-remitting multiple sclerosis, who developed acute anterior uvei...
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متن کامل[Cystoid macular oedema after fingolimod treatment in multiple sclerosis].
CASE REPORT A woman, treated with immunomodulatory and immunosuppressive drugs for multiple sclerosis, developed macular oedema 4 months after oral fingolimod administration. The patient was previously seen by an ophthalmologist, with a normal anterior segment and funduscopic examination. Four months after the treatment she referred to decreased visual acuity in both eyes. The funduscopic and O...
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ورودعنوان ژورنال:
- JAMA ophthalmology
دوره 131 1 شماره
صفحات -
تاریخ انتشار 2013